Pinnacle Biomedical Research Institute

Pinnacle Biomedical Research Institute (PBRI) was established by M. G. Nayak Memorial Educational Society (Registered by Government of Madhya Pradesh under Society registration act 1973) with a vision of disease free society. To accomplish this vision team of young researchers was constituted under the leadership of Prof. (Dr.) S. B. Kasture, well known for his contribution to neuropharmacology.

PBRI has well equipped laboratories of Pharmacology, Biotechnology, Microbiology, Immunology, Phytochemistry and Formulation-Development and sophisticated instruments PBRI is known for its quality research. Researchers of PBRI believe in interdisciplinary work, each laboratory works as a separate entity but the research moves from one lab to another.

 Prof S.B.Kasture (Director, PBRI) and Prof R. Singh (Director SPS, Shobhit University) signed MOU.

      Recent International Presentations

• Maria Assunta Frau, Andrea Maxia, Danilo Falconieri, Maria Cecilia Loi, Manvendra Singh Karchuli, Sanjay  Kasture, Essential oil of Myrtus communis L. (myrtaceae) inhibits IL-6 and TNF-α: a potential anti-inflammatory agent, International congress on aromatic and medicinal plants, CIPAM – 2011, 13-15 April, Cagliari, Italy

• Andrea Maxia, Maria Assunta Frau, Alessandra Piras, Cinzia Sanna, Manvendra Singh Karchuli, Veena Kasture, Pistacia lentiscus L. (anacardiaceae) essential oil inhibits cotton pellet granuloma in rats: involvement of IL-6 and TNF-α, International congress on aromatic and medicinal plants, CIPAM – 2011, 13-15 April, Cagliari, Italy

      Recent Publications

·         Antidepressant activity of Ceratonia siliqua L. fruit extract, a source of polyphenols, Natural Product Research, 2011,  25, 4, 450 – 456 

·         Anxiolytic activity of Ipomoea aquatica leaves, European Journal of Experimental Biology, 2011, 1 (1):63-70

·         To study diuretic activity of Passiflora Incarnata Leaves, Pharmacologyonline,  20111: 44-48

·         Antioxidant and Anticholinergic Activity of Rubia cordifolia, Pharmacologyonline 2, 2011 272-278

·         Phytochemical screening and antibacterial potential of chloform crude extract of Parkinsonia aculata Lin (Familiy-Leguminoseae) leaves against some bacteria acusing urinary tract infection (UTI) in humans, Internation Journal of Pharmaceutical Research and Development, 2011, 3 (6), 118-112

·         Evaluation of Immunomodulatory Activity of Hydroalcoholic Extract of Quisqualis indica Linn. Flower in Wistar rats, International Journal of Pharmacy & Life Sciences, 2011, 2, 4, 687-694

·         Formulation and evaluation of floating microspheres of boswellic acid, International journal of Pharm Tech Research, 2011, 3, 1, 76-81

·         In -Vitro antioxidative activity of phenolic and flavonoid compounds extracted from fruit of Garcinia indica, Int. J. of Pharm. & Life Sci. (IJPLS), 2011, 2, 3 , 613-616

·         Review on Hepatoprotective Plants, International Journal of Pharmaceutical Sciences Review and Research, 2011,  7, 1, 15-26

·         Anti-inflammatory activity of hydroalcoholic extract of Quisqualis indica Linn. flower in rats, Int. J. of Pharm. & Life Sci. (IJPLS), Vol. 2, Issue 8: Aug.: 2011, 977-981

·         Cardioprotective potential of Punica granatum extract in isoproterenol-induced myocardial infarction in Wistar rats, Journal of Pharmacology and Pharmacotherapeutics, 2010, 1, 1, 32-37

·         Effect of dopaminergic drugs on rivastigmine induced vacuous chewing movements and tongue protrusion in rats, Pharmacologyonline, 2010, 2: 412-415

·         Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic wistar rats, Phytotherapy Research, 2010, 24, S2,  S196–S203

·         Effect of Tamarindus Indica And Curcuma Longa on Stress Induced Alopecia, Pharmacologyonline, 2010, 1, 377-384

·         Self Emulsifying Drug Delivery System a Novel Approach for Enhancement of Bioavalibility, International Journal of Pharmtech Research, 2010, 2, 3, 1738-1745

·         Formulation and evaluation of biodegradable microspheres of tinidazole., International Journal of Drug Delivery. 2010;2(3):238-241

·         Protective effect of Solanum torvum on doxorubicin-induced nephrotoxicity in rats, Food and Chemical Toxicology, 2010, 48, 1, 436-440

·         Effect of Solanum torvum on blood pressure and metabolic alterations in fructose hypertensive rats, Journal of Ethnopharmacology, 126,  1, 29 October 2009, 86-89